Which protein acts as a major inhibitor of cyclin-CDK complexes during DNA damage?
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Correct answer: p53
p53 is a tumor suppressor protein that becomes activated in response to DNA damage. It induces CDK inhibitors, halting the cell cycle to allow repair.
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More Cell Cycle: Phases and Checkpoints questions
- The restriction point in G1 phase determines whether a cell:
- Which cyclin is primarily associated with mitosis?
- Which phase of mitosis involves alignment of chromosomes at the equatorial plate?
- What is the main function of CDKs in the cell cycle?
- Which checkpoint prevents cells with damaged DNA from entering S phase?
- In which phase does cytokinesis usually begin?