In the context of cancer, how do mutations in the p53 gene typically affect apoptosis?
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Correct answer: They disable a checkpoint that triggers apoptosis after DNA damage
p53 is a tumor suppressor that normally induces apoptosis if DNA damage is irreparable. Mutations in p53 prevent this programmed death, allowing damaged cells to survive and proliferate, contributing to tumor progression.
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More Apoptosis and Its Significance questions
- Which of the following is considered an anti-apoptotic protein?
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