In a beta-pleated sheet, the R-groups of the amino acids are positioned:
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Correct answer: Alternating above and below the plane of the sheet
In a beta-pleated sheet, R-groups project perpendicularly to the plane of the sheet, alternating above and below from one residue to the next. This arrangement minimizes steric clashes between adjacent side chains and stabilizes the extended beta-strand conformation through interstrand hydrogen bonds along the backbone.
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