What is the function of 'Molecular Chaperones' (such as Hsp70)?
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Correct answer: To assist correct folding of newly synthesized polypeptides
Molecular chaperones such as Hsp70 bind transiently to exposed hydrophobic segments of newly synthesized or stress-denatured polypeptides, preventing improper aggregation and guiding the protein toward its correct native conformation. They use ATP hydrolysis to drive repeated binding-and-release cycles.
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