Enzymes: Classification, Kinetics and Inhibition · Zoology

Competitive inhibition occurs when an inhibitor:

  1. Binds irreversibly to the enzyme active site
  2. Binds only to an allosteric regulatory site
  3. Competes with substrate for the active site
  4. Degrades and destroys the enzyme structure
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Correct answer: Competes with substrate for the active site

Competitive inhibitors structurally resemble the substrate and compete directly for binding at the active site. The inhibition is reversible and can be overcome by increasing substrate concentration; Vmax remains unchanged but Km increases.

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