Muscle Physiology: Contraction Mechanisms · Zoology

What occurs during the 'power stroke' phase of the sliding filament mechanism?

  1. ATP binds to the myosin head, causing it to detach from actin
  2. The myosin head hydrolyzes ATP to ADP and inorganic phosphate
  3. The myosin head pivots after releasing ADP and phosphate, pulling the actin filament
  4. Calcium is actively pumped back into the sarcoplasmic reticulum
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Correct answer: The myosin head pivots after releasing ADP and phosphate, pulling the actin filament

After a cross-bridge forms, the release of stored energy from the previous ATP hydrolysis causes the myosin head to bend toward the M-line. This movement slides the thin filament over the thick filament, shortening the sarcomere.

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