Thermoregulation and Body Fluids · USMLE Step 1

A mountaineer exposed to cold develops frostbite. Which mechanism contributes most to tissue damage?

  1. Increased metabolic heat production
  2. Vasodilation leading to fluid leakage
  3. Prolonged vasoconstriction reducing flow
  4. Accelerated sweating with evaporation
Show answer and explanation

Correct answer: Prolonged vasoconstriction reducing flow

Cold exposure triggers persistent vasoconstriction, reducing perfusion and leading to tissue ischemia. This causes frostbite injury.

Difficulty: Medium Question 13 of 20

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