Which parameter describes the theoretical volume that a drug would occupy if it were evenly distributed at the same concentration as in plasma?
Show answer and explanation
Correct answer: Volume of distribution
The apparent volume of distribution (Vd) represents the hypothetical volume into which the drug would distribute to yield the observed plasma concentration.
Practice all 20 Pharmacokinetics and Pharmacodynamics questions
Keep practicing
More Pharmacokinetics and Pharmacodynamics questions
- If a drug’s clearance increases while its volume of distribution remains constant, what happens to its elimination half-life (t½)?
- Which route of drug administration yields 100% bioavailability by definition?
- Which is most likely when a drug is highly lipophilic and has low plasma protein binding?
- What does the term Clearance (CL) refer to in pharmacokinetics?
- What does Pharmacodynamics (PD) study?
- A drug reaches steady-state concentration after chronic dosing. Approximately how many half-lives are required to reach ~95% of steady-stat…