What does the term Clearance (CL) refer to in pharmacokinetics?
Show answer and explanation
Correct answer: Plasma volume cleared of drug per unit time
Clearance defines the theoretical volume of plasma cleared of drug per unit time and determines elimination efficiency.
Practice all 20 Pharmacokinetics and Pharmacodynamics questions
Keep practicing
More Pharmacokinetics and Pharmacodynamics questions
- What does Pharmacodynamics (PD) study?
- A drug reaches steady-state concentration after chronic dosing. Approximately how many half-lives are required to reach ~95% of steady-stat…
- Which kinetic model is characterized by a constant rate of elimination, independent of drug concentration?
- Which parameter would most directly determine the loading dose required to rapidly achieve a target plasma concentration?
- An oral drug undergoes substantial first-pass metabolism in the liver. Which effect does this have on its pharmacokinetics?
- Which term refers to the fraction of drug unbound to plasma proteins and free to exert effect or be eliminated?