Genetic and Pediatric Diseases · USMLE Step 1

Which syndrome is caused by the complete or partial loss of one X chromosome in a genetically female individual and often results in short stature, infertility and congenital heart defects?

  1. Klinefelter syndrome
  2. Turner syndrome
  3. Down syndrome
  4. Fragile X syndrome
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Correct answer: Turner syndrome

Turner syndrome results from monosomy X (45, XO) and presents in females with short stature, gonadal dysgenesis (infertility), and frequent congenital cardiovascular anomalies.

Difficulty: Medium Question 7 of 20

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