Renal and Urinary: Glomerulonephritis, AKI · USMLE Step 1

A patient with lupus develops proteinuria and hematuria. Biopsy shows 'wire-loop' lesions. Which condition is this?

  1. Minimal change disease
  2. Membranoproliferative GN
  3. Lupus nephritis
  4. IgA nephropathy
Show answer and explanation

Correct answer: Lupus nephritis

Wire-loop lesions indicate immune complex deposition in lupus nephritis, especially in diffuse proliferative glomerulonephritis.

Difficulty: Medium Question 8 of 20

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