Renal and Urinary: Glomerulonephritis, AKI · USMLE Step 1

A patient with chronic lithium use presents with polyuria and hypernatremia. Which renal condition is most likely?

  1. Central diabetes insipidus
  2. Nephrogenic diabetes insipidus
  3. SIADH
  4. Adrenal crisis
Show answer and explanation

Correct answer: Nephrogenic diabetes insipidus

Lithium damages collecting ducts, causing nephrogenic diabetes insipidus with inability to concentrate urine.

Difficulty: Medium Question 14 of 20

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