Renal and Urinary: Glomerulonephritis, AKI · USMLE Step 1

A patient presents with rapidly progressive renal failure and crescent formation on biopsy. Which antibody is most likely present?

  1. Anti-dsDNA
  2. Anti-GBM
  3. Anti-centromere
  4. p-ANCA
Show answer and explanation

Correct answer: Anti-GBM

Anti-GBM antibodies cause Goodpasture syndrome, a form of RPGN with linear IgG deposition and crescent formation.

Difficulty: Medium Question 2 of 20

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