Musculoskeletal and Skin: Osteoporosis, Psoriasis · USMLE Step 1

Which factor increases a patient’s risk of developing osteoporosis?

  1. Long-standing obesity
  2. Late natural menopause
  3. Chronic glucocorticoid use
  4. Persistently high estrogen levels
Show answer and explanation

Correct answer: Chronic glucocorticoid use

Glucocorticoids decrease bone formation and increase bone resorption. Long-term use is a major secondary cause of osteoporosis.

Difficulty: Medium Question 3 of 20

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