Multisystem: Shock, Sepsis and Metabolic Syndromes · USMLE Step 1

A patient with sepsis develops disseminated intravascular coagulation (DIC). Which finding is most characteristic?

  1. Increased fibrinogen levels
  2. Thrombocytosis
  3. Widespread microthrombi and bleeding
  4. Increased antithrombin III activity
Show answer and explanation

Correct answer: Widespread microthrombi and bleeding

DIC results from systemic coagulation activation causing both thrombi and consumption of clotting factors. This leads to bleeding and organ damage.

Difficulty: Medium Question 13 of 19

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