Gastrointestinal: Liver Disease, IBD · USMLE Step 1

A patient with chronic hepatitis B develops hepatocellular carcinoma. Which marker is most specific for HCC?

  1. Anti-HBc IgM
  2. Alpha-fetoprotein
  3. AST:ALT ratio >2
  4. Prothrombin time
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Correct answer: Alpha-fetoprotein

Alpha-fetoprotein is elevated in hepatocellular carcinoma and is useful for monitoring disease progression.

Difficulty: Medium Question 6 of 20

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