Gastrointestinal: Liver Disease, IBD · USMLE Step 1

A man with ulcerative colitis has elevated p-ANCA. Which extraintestinal manifestation is most associated?

  1. Kidney stones
  2. Perianal fistulas
  3. Primary sclerosing cholangitis
  4. Oral aphthous ulcers
Show answer and explanation

Correct answer: Primary sclerosing cholangitis

Primary sclerosing cholangitis is strongly associated with UC and often presents with p-ANCA positivity.

Difficulty: Medium Question 5 of 20

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