Endocrine and Reproductive Disorders · USMLE Step 1

A woman presents with irregular menses and hirsutism. Labs show elevated LH:FSH ratio. Which condition is most likely?

  1. Primary ovarian insufficiency
  2. Polycystic ovarian syndrome
  3. Hyperprolactinemia
  4. Cushing syndrome
Show answer and explanation

Correct answer: Polycystic ovarian syndrome

PCOS is characterized by an elevated LH:FSH ratio, hyperandrogenism, and menstrual irregularities. Insulin resistance is also common.

Difficulty: Medium Question 4 of 20

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