What happens if a cell bypasses the spindle checkpoint despite improper spindle attachment during mitosis?
Show answer and explanation
Correct answer: Daughter cells receive unequal chromosome numbers, causing aneuploidy
Bypassing the spindle checkpoint can lead to mis-segregation of chromosomes during anaphase, producing daughter cells with abnormal chromosome numbers (aneuploidy), which can contribute to genomic instability.
Keep practicing
More Cell cycle and apoptosis questions
- Which event typically precedes activation of apoptosis in a cell with extensive DNA damage that cannot be repaired?
- Which phase of the cell cycle is characterized by DNA synthesis (duplication of the genome)?
- What is the primary role of cyclin-dependent kinases (CDKs) in the eukaryotic cell cycle?
- Which checkpoint prevents a cell with DNA damage from entering S phase, allowing time for repair or triggering cell death if damage is irre…
- What is the significance of the G0 phase in the cell cycle?
- Which of the following proteins is a key tumor suppressor that regulates both cell-cycle checkpoints and apoptosis in response to DNA damag…