Cell cycle and apoptosis · USMLE Step 1

What is the significance of the G0 phase in the cell cycle?

  1. It is the phase where genomic DNA synthesis takes place
  2. A quiescent, non-dividing resting state outside the cycle
  3. It marks the very onset of mitosis
  4. It is the phase during which cytokinesis occurs
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Correct answer: A quiescent, non-dividing resting state outside the cycle

G0 is a quiescent phase; cells that are terminally differentiated or not actively dividing enter G0 instead of re-entering G1, thus pausing the cell division cycle.

Difficulty: Medium Question 4 of 19

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