In a recessive disease, the carrier frequency is found to be approximately 1/25. What is the approximate disease prevalence?
Show answer and explanation
Correct answer: 1/2500
The carrier frequency 2pq is approximately 1/25. With p approximately 1, solving gives q approximately 1/50, so disease prevalence q-squared is approximately 1/2500.
Keep practicing
More Population genetics questions
- Directional selection acts on a population by:
- A population in which one allele becomes 100% prevalent has undergone:
- Which situation exemplifies genetic drift?
- Which event increases homozygosity within a population?
- In Hardy-Weinberg equilibrium, which term represents the frequency of heterozygotes?
- Which factor most strongly disrupts Hardy-Weinberg equilibrium by introducing new alleles?