Which of the following polymerases is primarily responsible for lagging-strand elongation in eukaryotic cells?
Show answer and explanation
Correct answer: DNA polymerase δ
In eukaryotes, DNA polymerase δ is the main polymerase responsible for lagging-strand synthesis, while polymerase ε largely handles leading-strand synthesis.
Keep practicing
More DNA Structure and Replication questions
- What problem at the ends of linear eukaryotic chromosomes is addressed by the enzyme telomerase during replication?
- What is the role of single-stranded DNA binding proteins (SSBs) during replication?
- During DNA replication, which enzyme replaces RNA primers on the lagging strand with DNA in prokaryotes?
- Which of the following is NOT required for formation of the replication fork during DNA replication?
- Which feature of DNA’s structure provides the chemical basis for the semiconservative replication mechanism?
- If a toxin specifically inhibited DNA primase, which process would be directly impaired during DNA replication?