Lung Volumes and Capacities · Physiology

Closing Volume (CV) is the volume of air remaining in the lungs when:

  1. Small airways in the lower dependent parts of the lungs begin to close
  2. The glottis closes during a Valsalva maneuver
  3. The volume reaches the Functional Residual Capacity
  4. The surfactant stops working
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Correct answer: Small airways in the lower dependent parts of the lungs begin to close

Closing volume occurs during expiration when the intrapleural pressure exceeds the airway pressure in the dependent (lower) regions of the lung, causing small airways to collapse. This volume typically increases with age and smoking.

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