Loop diuretics impair urine concentration by inhibiting:
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Correct answer: Na-K-2Cl transporter
Loop diuretics block the Na-K-2Cl transporter in the thick ascending limb. This disrupts the medullary osmotic gradient.
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More Urine Concentration and Dilution questions
- The maximum concentrating ability of human kidneys produces urine osmolality of approximately:
- The primary mechanism responsible for urine concentration in the kidney is the:
- Which segment of the nephron is impermeable to water but actively transports sodium chloride?
- The descending limb of the loop of Henle is characterized by:
- Antidiuretic hormone (ADH) primarily increases water permeability in the:
- In the absence of ADH, the kidney produces urine that is: