Digestive System Overview · Physiology

Where are the 'Stem Cells' of the small intestine located, which are responsible for the constant renewal of the epithelial lining every 3 to 5 days?

  1. At the tips of the villi
  2. In the submucosal glands
  3. In the Crypts of Lieberkühn
  4. Within the Peyer's patches
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Correct answer: In the Crypts of Lieberkühn

Intestinal stem cells reside in the base of the intestinal crypts (Crypts of Lieberkühn). As they divide, new cells migrate upward toward the villus tips, differentiating into enterocytes, goblet cells, and endocrine cells along the way.

Difficulty: Medium Question 34 of 39

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