Anaemia types and causes · Physiology

Sickle cell anaemia is caused by a defect in:

  1. Heme ring synthesis
  2. Globin chain structure
  3. Duodenal iron absorption
  4. Bone marrow stromal function
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Correct answer: Globin chain structure

Sickle cell anaemia is due to a mutation in the beta-globin gene. This produces abnormal hemoglobin S.

Difficulty: Medium Question 9 of 20

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