Which of the following drugs is a 'thiazide-like' diuretic with a significantly longer half-life than Hydrochlorothiazide?
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Correct answer: Chlorthalidone
Chlorthalidone is a thiazide-like diuretic with a half-life of 40–60 hours, compared to 6–15 hours for hydrochlorothiazide. Its long duration of action provides more consistent 24-hour blood pressure control.
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