Antiplatelet Drugs · Pharmacology

Which of the following agents is a synthetic heptapeptide that reversibly inhibits the Glycoprotein IIb/IIIa receptor?

  1. Abciximab (Fab fragment, ReoPro)
  2. Eptifibatide (Integrilin)
  3. Tirofiban (Aggrastat)
  4. Cilostazol (Pletal)
Show answer and explanation

Correct answer: Eptifibatide (Integrilin)

Eptifibatide is a cyclic heptapeptide derived from rattlesnake venom. It acts as a reversible competitive antagonist at the GP IIb/IIIa receptor and has a much shorter duration of action than Abciximab.

Difficulty: Medium Question 10 of 20

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