Which antiplatelet drug can cause a rare but serious side effect known as Thrombotic Thrombocytopenic Purpura (TTP)?
Show answer and explanation
Correct answer: Clopidogrel
While very rare, TTP has been reported with the use of thienopyridines like Clopidogrel and Ticlopidine. It is a medical emergency characterized by thrombocytopenia, hemolytic anemia, and neurological symptoms.
Keep practicing
More Antiplatelet Drugs questions
- What is the primary effect of Thromboxane A2 (TXA2) on blood vessels?
- Which P2Y12 inhibitor is available in an intravenous formulation for rapid platelet inhibition during PCI?
- Ticlopidine is rarely used today primarily due to the risk of which hematologic toxicity?
- Which of the following drugs is a non-peptide, small molecule mimetic that reversibly inhibits the GP IIb/IIIa receptor?
- Platelet activation involves the release of granules containing which substances that further amplify aggregation?
- Why does low-dose Aspirin (81mg) exhibit selectivity for inhibiting platelet COX-1 over systemic COX-2?