A patient with schizophrenia is concerned about sexual side effects and weight gain. Which of the following antipsychotics is least likely to cause hyperprolactinemia?
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Correct answer: Aripiprazole
Aripiprazole, due to its partial agonism, does not cause the profound D2 blockade in the tuberoinfundibular pathway seen with other agents. It is also considered relatively weight-neutral compared to drugs like Olanzapine.
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