Organophosphate toxicity primarily results from inhibition of which enzyme?
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Correct answer: Acetylcholinesterase
Organophosphates irreversibly inhibit acetylcholinesterase, leading to accumulation of acetylcholine at synapses. This causes overstimulation of muscarinic and nicotinic receptors.
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More Organophosphate Toxicity questions
- Which of the following is a classic muscarinic manifestation of organophosphate poisoning?
- Which antidote competitively blocks muscarinic receptors in organophosphate poisoning?
- Pralidoxime is effective in organophosphate poisoning because it:
- Which symptom represents a nicotinic effect of organophosphate toxicity?
- Which mnemonic describes muscarinic symptoms of organophosphate poisoning?
- Which of the following is a central nervous system manifestation of severe organophosphate toxicity?