Prazosin is primarily used in the treatment of hypertension and Benign Prostatic Hyperplasia (BPH) due to its selective antagonism of which receptor?
Show answer and explanation
Correct answer: Alpha-1
Prazosin selectively blocks alpha-1 receptors on vascular smooth muscle and the bladder neck/prostate. This results in vasodilation to lower blood pressure and relaxation of smooth muscle to improve urine flow.
Keep practicing
More Adrenergic Antagonists questions
- Which selective beta-1 antagonist is known for having a very short half-life (approximately 10 minutes) and is administered intravenously f…
- What is the primary mechanism by which non-selective beta-blockers, like Propranolol, can worsen respiratory function in asthmatic patients?
- Which of the following drugs is a selective alpha-2 antagonist that has been historically used for the treatment of erectile dysfunction bu…
- A patient is prescribed Tamsulosin for symptomatic relief of BPH. Why is this drug preferred over Prazosin for this condition?
- What is the physiological significance of 'Intrinsic Sympathomimetic Activity' (ISA) in beta-blockers like Pindolol?
- Which of the following is a selective beta-1 blocker that also stimulates the release of nitric oxide, leading to vasodilation?