Adrenergic Agonists · Pharmacology

Which of the following is an indirect-acting sympathomimetic that works by displacing stored norepinephrine from synaptic vesicles into the synaptic cleft?

  1. Cocaine
  2. Tyramine
  3. Oxymetazoline
  4. Ritodrine
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Correct answer: Tyramine

Tyramine, found in fermented foods, enters the nerve terminal and displaces norepinephrine from vesicles. This can lead to a 'hypertensive crisis' in patients taking MAO inhibitors.

Difficulty: Medium Question 8 of 20

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