Which fluoroquinolone is unique because it does not require dose adjustment in renal failure due to its primary elimination via the liver?
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Correct answer: Moxifloxacin
Moxifloxacin is primarily metabolized by the liver and excreted in the bile/feces. Because it is not significantly cleared by the kidneys, it is the only major fluoroquinolone that does not require adjustment for renal impairment.
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