Aminoglycosides can cause a rare but serious neuromuscular blockade. This effect is most likely to occur in patients with which underlying condition?
Show answer and explanation
Correct answer: Myasthenia Gravis
Aminoglycosides can inhibit the pre-junctional release of acetylcholine and decrease post-junctional sensitivity. This can exacerbate muscle weakness in patients with Myasthenia Gravis or those receiving neuromuscular blockers.
Keep practicing
More Aminoglycosides questions
- If neuromuscular blockade occurs due to aminoglycoside administration, which of the following is the preferred pharmacological reversal age…
- Which parameter of the 'killing curve' defines the efficacy of aminoglycosides?
- A patient on Gentamicin develops a high-pitched tinnitus and vertigo. Which part of the ear is likely damaged?
- Tobramycin is frequently administered via inhalation (nebulizer) for patients with which condition?
- Aminoglycosides are primarily eliminated from the body by which route?
- Which of the following is an early sign of aminoglycoside-induced nephrotoxicity?