Which gene is a classic example of a tumor suppressor involved in cell cycle regulation?
Show answer and explanation
Correct answer: TP53
TP53 encodes the p53 protein, which regulates the cell cycle and promotes DNA repair or apoptosis in response to damage. Loss of TP53 function is common in many cancers.
Keep practicing
More Molecular Pathology of Cancer questions
- The two-hit hypothesis primarily applies to which class of genes?
- A point mutation in the RAS gene typically leads to:
- Which chromosomal translocation is characteristic of chronic myeloid leukemia?
- Amplification of the HER2 gene is most commonly associated with which cancer?
- Loss of function of the RB gene primarily disrupts which cell cycle checkpoint?
- Which DNA repair defect is characteristic of Lynch syndrome?