Fungal Infections · Pathology

A patient with uncontrolled diabetes mellitus presents with a rapidly progressing necrotic lesion of the nasal turbinates. Histology shows broad, ribbon-like, non-septate hyphae with right-angle branching. What is the most likely diagnosis?

  1. Aspergillosis
  2. Mucormycosis
  3. Candidiasis
  4. Histoplasmosis
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Correct answer: Mucormycosis

Mucormycosis (caused by Rhizopus or Mucor) is characterized by wide, pauciseptate hyphae that branch at 90-degree angles. It is notorious for angioinvasion and tissue infarction, especially in ketoacidotic patients.

Difficulty: Medium Question 2 of 20

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