Bacterial Infections · Pathology

Which bacterium is known for causing 'Whooping Cough' by paralyzing the ciliary escalator via tracheal cytotoxin?

  1. Legionella pneumophila
  2. Bordetella pertussis
  3. Klebsiella pneumoniae
  4. Mycoplasma pneumoniae
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Correct answer: Bordetella pertussis

Bordetella pertussis produces several toxins, including pertussis toxin and tracheal cytotoxin. Tracheal cytotoxin specifically damages ciliated epithelial cells, leading to impaired mucus clearance and the characteristic paroxysmal cough.

Difficulty: Medium Question 13 of 20

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