Iron Deficiency Anemia · Pathology

Which of the following decreases the absorption of non-heme iron in the diet?

  1. Ascorbic acid (Vitamin C)
  2. Citric acid
  3. Tannins in tea and coffee
  4. Gastric acid
Show answer and explanation

Correct answer: Tannins in tea and coffee

Tannins, phytates (in grains), and oxalates bind to non-heme iron in the gut, forming insoluble complexes that cannot be absorbed. Conversely, Vitamin C and gastric acid facilitate absorption by keeping iron in its more soluble ferrous (Fe2+) state.

Difficulty: Medium Question 17 of 20

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