Anemia Classification · Pathology

The presence of 'Bite cells' and 'Heinz bodies' is characteristic of which hemolytic process?

  1. Paroxysmal Nocturnal Hemoglobinuria (PNH)
  2. G6PD deficiency
  3. Autoimmune Hemolytic Anemia
  4. Pyruvate Kinase deficiency
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Correct answer: G6PD deficiency

Heinz bodies are denatured hemoglobin precipitates caused by oxidative stress in G6PD deficiency. As these cells pass through the spleen, macrophages pluck out the inclusions, leaving 'bite cells'.

Difficulty: Medium Question 15 of 20

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