Reversible and Irreversible Cell Injury · Pathology

Which specific nuclear change is characterized by the fragmentation of a pyknotic nucleus?

  1. Autophagy
  2. Karyolysis
  3. Karyorrhexis
  4. Apoptosis
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Correct answer: Karyorrhexis

Karyorrhexis is the stage of nuclear death where the pyknotic nucleus undergoes fragmentation. This follows pyknosis (nuclear shrinkage) and precedes karyolysis (fading of chromatin).

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