Reversible and Irreversible Cell Injury · Pathology

Which of the following is an anti-apoptotic protein that prevents the release of cytochrome c from mitochondria?

  1. Caspase-3
  2. Bak
  3. Bax
  4. Bcl-2
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Correct answer: Bcl-2

Bcl-2 is the prototypical anti-apoptotic protein that resides in the mitochondrial membranes. It acts by inhibiting the pro-apoptotic proteins Bax and Bak, thereby maintaining membrane integrity and preventing the leakage of cytochrome c.

Difficulty: Medium Question 8 of 20

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