Peptic Ulcer Disease · Pathology

Which of the following is true regarding the risk of malignancy in peptic ulcers?

  1. Duodenal ulcers have a high risk of becoming cancer
  2. Gastric ulcers require biopsy to exclude cancer
  3. NSAID-induced ulcers are more likely to be malignant
  4. Ulcers in the fundus are never malignant
Show answer and explanation

Correct answer: Gastric ulcers require biopsy to exclude cancer

Duodenal ulcers are virtually never malignant. However, because gastric ulcers can be the presenting form of a gastric adenocarcinoma, endoscopic biopsy is mandatory for all gastric ulcers.

Difficulty: Medium Question 16 of 20

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