Peptic Ulcer Disease · Pathology

The Urea Breath Test for H. pylori detection is based on the production of which substance by the bacteria?

  1. H. pylori urease
  2. Lactic acid
  3. Hydrogen sulfide
  4. Cytotoxin-associated gene A (CagA)
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Correct answer: H. pylori urease

H. pylori produces the enzyme urease, which breaks down urea into ammonia and carbon dioxide. In the test, labeled urea is ingested, and the presence of labeled CO2 in the breath confirms the infection.

Difficulty: Medium Question 17 of 20

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