Skin Biopsy Interpretation · Pathology

Which pattern is characteristic of cutaneous lupus erythematosus?

  1. Acantholysis
  2. Interface dermatitis with thickened basement membrane
  3. Keratin pearl formation
  4. Pure neutrophilic infiltrate
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Correct answer: Interface dermatitis with thickened basement membrane

Cutaneous lupus erythematosus shows interface dermatitis with basal vacuolar change and thickening of the basement membrane. Dermal mucin deposition is also common.

Difficulty: Medium Question 10 of 20

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