Skin Biopsy Interpretation · Pathology

Which histologic feature is typical of basal cell carcinoma?

  1. Keratin pearls
  2. Peripheral palisading of tumor cells
  3. Sheets of melanocytes
  4. Granuloma formation
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Correct answer: Peripheral palisading of tumor cells

Basal cell carcinoma shows nests of basaloid cells with peripheral palisading and stromal retraction. It arises from basal epidermal cells.

Difficulty: Medium Question 6 of 20

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