Which histologic feature is most characteristic of psoriasis on skin biopsy?
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Correct answer: Acanthosis with elongation of rete ridges and parakeratosis
Psoriasis shows regular acanthosis with elongated rete ridges, thinning of suprapapillary plates, and parakeratosis. Neutrophils in the stratum corneum (Munro microabscesses) are also typical.
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