Inflammatory Skin Disorders · Pathology

A skin biopsy from a patient with Discoid Lupus Erythematosus (DLE) would most likely show:

  1. Subepidermal neutrophilic infiltrate
  2. Epidermal atrophy, follicular plugging, and BM thickening
  3. Diffuse dermal eosinophilic infiltration
  4. Regular psoriasiform acanthosis with 'Munro microabscesses'
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Correct answer: Epidermal atrophy, follicular plugging, and BM thickening

DLE is characterized by an interface dermatitis that leads to epidermal atrophy. It also features prominent plugging of hair follicles with keratin and thickening of the underlying basement membrane.

Difficulty: Medium Question 16 of 20

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