A 65-year-old male presents with a new-onset holosystolic murmur 4 days after an inferior wall MI. Which of the following is the most likely cause?
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Correct answer: Papillary muscle rupture
Papillary muscle rupture is a critical complication often following inferior MIs (supplied by the RCA). It leads to acute, severe mitral regurgitation and a holosystolic murmur, often resulting in rapid heart failure.
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