Atherosclerosis · Pathology

Foam cells in atherosclerotic plaques are derived primarily from:

  1. Endothelial cells
  2. Smooth muscle cells
  3. Activated macrophages
  4. Neutrophils
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Correct answer: Activated macrophages

Foam cells are formed when macrophages ingest oxidized LDL cholesterol. These lipid-laden macrophages accumulate within the intima to form fatty streaks.

Difficulty: Medium Question 3 of 20

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